在管理电子邮件方面，Outlook是Windows用户喜欢的最佳伴侣。与其他电子邮件程序相比，作为Microsoft Office一部分的Outlook具有许多功能。^(Outlook)但是，在某些情况下，如果Outlook配置错误，它将无法启动。今天，我们将讨论一个这样的问题，我们遇到以下错误消息，Outlook只是拒绝启动：

Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened, The information store could not be opened, The operation failed.

如果您不断收到以下消息无法启动 Microsoft Outlook，^{(Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened)}则尝试启动Microsoft Outlook可能是一项艰巨的任务。无法打开 Outlook 窗口。无法打开该组文件夹。

Microsoft Outlook中出现此问题的原因尚不清楚。但是，出现此错误的主要原因是Outlook PST文件损坏或导航窗格^{(Navigation Pane)}设置文件损坏 - myprofile.XML，其中“myprofile”是Outlook配置文件名称。您如何确定您的Outlook文件是否已损坏？很简单^(Simple)，有问题的文件显示 0 KB 大小。

无法启动 Microsoft Outlook

收到此奇怪错误后，您可能会尝试重新启动系统并检查问题是否自行解决。您也可以尝试在兼容模式下运行Outlook，看看是否有帮助。如果您已经在兼容模式下^{(Compatibility Mode)}运行它，请将其关闭并查看。对于某些用户，它可能会自行解决，而对于其他用户，则需要应用修复。以下是可以帮助您摆脱此问题的方法：

1]以安全模式启动Outlook

打开运行框，键入outlook /safe并按 Enter 以在安全模式下打开 Outlook^{(open Outlook in Safe Mode)}。

如果它正常打开，那么您可能需要查看一些可能阻止Outlook的插件或扩展并将其删除。

您可以通过两种方式进行尝试。您可以禁用所有内容，然后逐个禁用它，或者您可以禁用一个并重新启动Outlook以检查一切是否正常。如果没有，你已经发现了问题。

• 单击^(Click)文件^(File)> 选项以打开Outlook选项^{(Outlook Options)}窗口。
• 选择加载项^(Add-ins)部分，它将显示列表。
• 在本节的底部，单击Manage Comm Ad-ins^{(Manage Comm Ad-ins)}旁边的 Go 按钮。
• 在这里，您可以取消选择要禁用的插件并重新启动Outlook。

2]在Outlook中^(Outlook)关闭^(Turn)兼容^{(Compatibility)}模式

检查Outlook是否在兼容模式下运行。Microsoft Outlook中的^{(Microsoft Outlook)}兼容^{(Compatibility)}模式旨在帮助程序在较旧的操作系统上运行。如果Outlook在兼容模式下运行，您可以将其关闭并查看它是否可以解决问题。

在您的计算机上找到Outlook.exe文件。

如果您运行的是最新版本的Office软件，您将在此处找到

C:\Program Files\Microsoft Office\root\Office16

或

C:\Program Files (x86)\Microsoft Office\root\Office16

找到后，右键单击Outlook.exe文件，选择“属性^(Properties)”选项，然后选择“兼容性^{(Compatibility)}”选项卡。

如果选中了“兼容性^{(Compatibility)}”选项卡上的任何框，请取消选中它们，然后选择“应用”>“确定”。

重新启动 Outlook^{(Restart Outlook)}。问题应该得到解决。

3]重置^(Reset)Outlook导航^(Outlook)窗格

按Windows Key + R“运行”^(Run)框中键入以下内容，然后按 Enter^(Enter)键：

Outlook.exe /resetnavpane

当您按 Enter^(Enter)键时，Outlook将启动并重置配置文件设置。运行此命令将清除并重新生成当前Outlook配置文件的导航窗格。这应该可以为您解决，否则请尝试下一个修复。

4]创建一个新的Outlook配置文件

打开控制面板^{(Control Panel)}。在搜索框中输入邮件^(mail)，然后按 Enter。

单击出现的邮件^{( Mail)}图标。在邮件设置 - Outlook^{(Mail Setup – Outlook)}窗口中，单击显示配置文件^{(Show Profiles)}选项。

在“邮件”^(Mail)窗口中，添加^(Add)您的新配置文件。然后选择始终使用此配置文件^{(Always use this profile)}并从下拉列表中选择您新添加的配置文件。

单击应用^(Apply)，然后单击确定^(OK)。

您现在可以重新启动Windows PC 并检查您现在是否可以打开Outlook。

Good luck!

有关 Outlook 疑难解答的更多信息：^{(More on Outlook troubleshooting:)}

1. Outlook 问题，如冻结、损坏的 PST、配置文件、加载项等。
2. Outlook^(N)中未实现错误^{(ot Implemented error in Outlook)}
3. Microsoft Outlook 卡在加载配置文件上^{(Microsoft Outlook stuck on Loading Profile)}
4. 将 Outlook 重新连接到 Outlook.com 以实现不间断的电子邮件访问
5. 将 Microsoft Outlook 客户端重新连接到 Outlook.com 后解决问题
6. Microsoft Outlook 遇到问题需要关闭
7. 操作失败，找不到对象
8. Outlook 中的电子邮件不同步
9. Outlook 没有响应、已停止工作、冻结或挂起^{(Outlook is not responding, has stopped working, freezes or hangs)}
10. 升级到 Windows 10 后无法访问 PST 文件或启动 Outlook。

Cannot start Microsoft Outlook, Cannot open the Outlook window

When it comes to managing emails, Outlook is the best companion a Windows user prefers. Outlook as a part of Microsoft Office has lots of features as compared to other email programs. However, in some situations, if Outlook gets misconfigured, it won’t start. Today, we’ll discuss one such issue, where we came around following error message, where Outlook simply refuses to start:

Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened, The information store could not be opened, The operation failed.

Trying to start Microsoft Outlook can be quite a task if you keep getting the following message Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened.

There’s no known cause as to why this problem occurs in Microsoft Outlook. However, the primary reason that can be attributed to the appearance of this error is either corrupt Outlook PST file or corrupt Navigation Pane settings file – myprofile.XML, where ‘myprofile’ is Outlook profile name. How do you find if your Outlook file is probably corrupt? Simple, the file in question shows 0 KB size.

Cannot start Microsoft Outlook

Upon receiving this strange error, you might try to restart your system and check if the issue fixes itself. You can also try to run Outlook in compatibility mode and see if this helps. If you are already running it in Compatibility Mode, turn it off and see. For some users, it may resolve itself, while for others, a fix is needed to be applied. Here are the ways, which could help you to get rid of this issue:

1] Start Outlook in Safe Mode

Open Run box, type outlook /safe and hit Enter to open Outlook in Safe Mode.

If it opens properly, then maybe you need to take a look at some addins or extensions that may be blocking Outlook and remove them.

You can try this in two ways. You can either disable everything and then it on one by one or, you can disable one and relaunch Outlook to check if everything is working fine. If not, you have found the problem.

• Click on File > Options to open the Outlook Options window.
• Select the Add-ins section, and it will reveal the list.
• At the bottom of this section.,  click on the Go button next to Manage Comm Ad-ins.
• Here you can unselect the addons you want to disable and relaunch Outlook.

2] Turn off Compatibility mode in Outlook

Check if Outlook is running in compatibility mode. Compatibility mode in Microsoft Outlook is designed to help a program run on an older operating system. If Outlook is running in compatibility mode, you can turn it off and see if it fixes the problem.

Find the Outlook.exe file on your computer.

If you are running the latest version of Office software, you will find it here

C:\Program Files\Microsoft Office\root\Office16

or at

C:\Program Files (x86)\Microsoft Office\root\Office16

When found, right-click the Outlook.exe file, select Properties option, and then choose the Compatibility tab.

If any of the boxes on the Compatibility tab are checked, uncheck them, then choose ‘Apply’ > OK.

Restart Outlook. The problem should get resolved.

3] Reset the Outlook navigation pane

Press Windows Key + R and type following into the Run box, hit Enter key then:

Outlook.exe /resetnavpane

When you hit Enter key, Outlook will be started with resetting the profile settings.  Running this command will clear and regenerate the navigation pane for the current Outlook profile. This should fix for you, else try the next fix.

4] Create a new Outlook profile

Open Control Panel. Type mail in the search box and hit Enter.

Click on the Mail icon which appears. In the Mail Setup – Outlook window, click Show Profiles option.

In the Mail window, Add your new profile. Then choose Always use this profile and select your newly added profile from drop down.

Click Apply followed by OK.

You can now restart your Windows PC and check if you can now open Outlook.

Good luck!

More on Outlook troubleshooting:

1. Outlook problems like freezing, corrupt PST, Profile, Add-in, etc.
2. Not Implemented error in Outlook
3. Microsoft Outlook stuck on Loading Profile
4. Reconnect Outlook to Outlook.com for uninterrupted email access
5. Troubleshoot issues after reconnecting Microsoft Outlook client to Outlook.com
6. Microsoft Outlook Encountered A Problem And Needs To Close
7. The operation failed, An object cannot be found
8. Email in Outlook not syncing
9. Outlook is not responding, has stopped working, freezes or hangs
10. Unable to access PST File or start Outlook after upgrading to Windows 10.

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