我最近在笔记本电脑上使用Microsoft Outlook时遇到了问题。它有Windows 7，我目前正在使用 Office 2010。我去打开Outlook，我收到以下错误：
Cannot start Microsoft Office Outlook. Cannot open the Outlook window.
我之前在我的机器上没有遇到过任何Office问题，所以这有点奇怪。我安装了一些应用程序并安装了一些Windows更新，但除此之外，一切都一样。如果您遇到同样的问题，请阅读下面的可能解决方案，看看它是否适合您。
方法 1 – 损坏的配置文件
有一个名为 profilename.xml 的文件存储Outlook中(Outlook)导航窗格(Navigation Pane)的设置。如果这已损坏（可能为 0 kb），则可能导致Outlook无法正常打开。该文件在Windows XP和Windows Vista/7上的位置是：
XP - C:Documents and Settings\Application Data\Microsoft\Outlook
Vista/7 - C:UsersAppDataRoamingMicrosoftOutlook
要解决此问题，您只需重置导航窗格文件。您可以通过转到开始(Start)然后运行(Run)或在Windows 7中单击开始(Start)然后在搜索框中键入运行来执行此操作。(Run)然后输入以下命令：
现在继续尝试再次启动Outlook，看看问题是否已经消失。如果没有，请继续尝试以下其他可能的解决方案。
方法 2 (Method 2) – 关闭缓存 Exchange 模式(– Turn Off Cached Exchange Mode)
如果您在办公环境中使用Exchange和Outlook，则此问题可能是由称为缓存 Exchange 模式(Cached Exchange Mode)的东西引起的。这基本上存储了您的Exchange(Exchange)邮箱的本地副本，这在笔记本电脑上很有用，但在始终连接的桌面上却没有用。如果您不需要缓存本地副本，请将其关闭，您应该不会再收到错误消息。以下是在Outlook(Outlook 2007) 2007、2010、2013和 2016中关闭缓存 Exchange 模式的链接。(Cached Exchange Mode)
Outlook 2013/2016
展望 2010(Outlook 2010)
展望 2007(Outlook 2007)
当您甚至不使用Microsoft Exchange时，您也可能会收到此“Exchange”错误。然后您可以安全地关闭缓存模式，一切都会正常工作。
方法 3 – 使用 ScanPST.exe
如果上述两种方法对您不起作用，那么您的实际PST文件可能存在问题。在这种情况下，扫描PST是修复问题的最佳选择。您可以阅读以下文章，其中详细介绍了如何在Outlook 2003、2007、2010、2013(Outlook 2003)和 2016中使用 scanpst 。
http://www.howto-outlook.com/faq/usingscanpst.htm
方法 4 – 创建一个新的配置文件
如果您有一个损坏的配置文件，您将不断收到此错误，直到您创建一个新的配置文件。您可以通过转到控制面板(Control Panel )，然后转到邮件(Mail)，然后显示配置文件(Show Profiles)，然后删除所有当前配置文件来做到这一点。但是，在删除任何配置文件之前，请确保备份您的PST文件。
方法 5(Method 5) – 启动不带扩展名的(No Extensions)Outlook(– Start Outlook)
另一个问题可能是第三方加载项。您可以通过启动不带扩展名的Outlook来测试这一点。您可以像我们上面所做的那样再次转到“运行”对话框来执行此操作，这次输入以下内容：(Run)
outlook.exe /noextensions
如果Outlook启动正常，那么您需要进入加载项管理器并禁用所有加载项，然后一次重新启用它们以查看是哪一个导致Outlook出现问题。
方法 6 – Outlook 连接器
如果您尝试在Outlook中设置(Outlook)Windows Live Hotmail ，您可能还会收到如下所示的消息：
Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened. An unexpected error has occured. MAPI was unable to load the information service msncon.dll. Be sure the service is correctly installed and configured.
在这种情况下，这是Outlook Connector的问题。您必须卸载它并重新安装它。你可以在这里下载：
32 位 - http://www.microsoft.com/download/en/details.aspx?id=24677
64 位 - http://office.microsoft.com/en-us/outlook/microsoft-office-outlook-hotmail-connector-overview-HA010222518.aspx
这绝对可以解决Hotmail用户的问题。
方法 7 – 默认网关
如果由于某种原因，您的计算机上没有默认网关设置，您也可能会收到此错误！不太确定为什么这很重要，但显然确实如此。幸运(Luckily)的是，Microsoft已经为您下载了一个Fix It，它将向您的计算机添加适当的注册表项来解决问题。
https://support.microsoft.com/en-us/help/913843/error-messages-when-you-try-to-connect-outlook-2007-to-exchange-serverhttp://support.microsoft.com/kb/913843
希望上述方法之一可以解决您的问题。如果没有，请在此处发表评论，并附上您的Office版本、操作系统和任何其他相关详细信息。享受！
Fix “Cannot Start Microsoft Office Outlook” Error
I recently ran into a problem whеn using Microsoft Outlook on mу laptoр. It’s got Windows 7 and I am using Office 2010 at the moment. I went to oрen Outlook and I got the following error:
Cannot start Microsoft Office Outlook. Cannot open the Outlook window.
I hadn’t run into any problems with Office on my machine before, so this was a little strange. I had installed a few apps and installed some Windows updates, but other than that, everything was the same. If you’re having the same problem, read the possible solutions below and see if it works for you.
Method 1 – Corrupt Profile
There is a file called profilename.xml that stores the settings for the Navigation Pane in Outlook. If this becomes corrupted (it might be 0 kb), then it can cause Outlook not to open properly. The location of the file on Windows XP and Windows Vista/7 is:
XP – C:\Documents and Settings\Application Data\Microsoft\Outlook
Vista/7 – C:\Users\AppData\Roaming\Microsoft\Outlook
To fix the problem, you just have to reset the nav pane file. You can do this by going to Start and then Run or in Windows 7, clicking on Start and then typing in Run in the search box. Then type in the following command:
Now go ahead and try to startup Outlook again and see if the issue has gone away. If not, continue to try the other possible solutions below.
Method 2 – Turn Off Cached Exchange Mode
If you are in an office environment and you’re using Exchange with Outlook, then this problem can be caused by something called Cached Exchange Mode. This basically stores a local copy of your Exchange mailbox, which is useful on a laptop, but not on a desktop that is always connected. If you don’t need a local copy cached, then turn this off and you should no longer get the error. Below are the links to turn off Cached Exchange Mode in Outlook 2007, 2010, 2013 and 2016.
Outlook 2013/2016
Outlook 2010
Outlook 2007
You may also get this “Exchange” error when you don’t even use Microsoft Exchange. Then you can safely turn off the cached mode and things will work fine.
Method 3 – Use ScanPST.exe
If the two methods above didn’t work for you, then you might have a problem with your actual PST file. In this case, scanPST is your best option to repair the problem. You can read the following post which goes into great detail on how to use scanpst with Outlook 2003, 2007, 2010, 2013 and 2016.
http://www.howto-outlook.com/faq/usingscanpst.htm
Method 4 – Create a New Profile
If you have a corrupt profile, you will keep getting this error until you create a new profile. You can do that by going to Control Panel and then Mail and then Show Profiles and then deleting all the current profiles. Before you delete any profiles, however, make sure you backup your PST file.
Method 5 – Start Outlook with No Extensions
Another issue could be a third-party add-in. You can test this out by starting Outlook with no extensions. You can do this by going to the Run dialog again like we did above and this time typing the following:
outlook.exe /noextensions
If Outlook starts fine, then you need to go into the add-in manager and disable all the add-ins and then re-enable them one at a time to see which one is causing the problem with Outlook.
Method 6 – Outlook Connector
You may also get a message that looks like this if you are trying to setup Windows Live Hotmail in Outlook:
Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened. An unexpected error has occured. MAPI was unable to load the information service msncon.dll. Be sure the service is correctly installed and configured.
In this case, it’s a problem with the Outlook Connector. You have to uninstall it and reinstall it. You can download it here:
32-bit – http://www.microsoft.com/download/en/details.aspx?id=24677
64-bit – http://office.microsoft.com/en-us/outlook/microsoft-office-outlook-hotmail-connector-overview-HA010222518.aspx
That should definitely fix your problem for Hotmail users.
Method 7 – Default Gateway
You can also get this error if, for some reason, you don’t have a default gateway setup on your computer! Not really sure why that would matter, but apparently it does. Luckily, Microsoft already has a Fix It for you download that will add the appropriate registry key to your computer to fix the problem.
https://support.microsoft.com/en-us/help/913843/error-messages-when-you-try-to-connect-outlook-2007-to-exchange-serverhttp://support.microsoft.com/kb/913843
Hopefully, one of the methods above fixes your problem. If not, post a comment here with your version of Office, OS, and any other relevant details. Enjoy!
